Pelargonium odoratissimum is a perennial and relatively flat-growing shrub, with highly scented leaves belongs to Geraniaceae family. The pelargonium species are native to South Africa that cultivated around the world as a popular ornamental and for its sweet leaves, aromatic scent and essential oil. The plant rarely grows beyond a height of 30 cm. The main stem is coarse and scaly due to persistent bases of old stipules. The roots are somewhat tuberous. The leaves, 30-40 mm in diameter, are roundish to ovate-cordate with crenulate margins. They are apple green and covered with fine short hairs making them pleasant to touch. They have a strong apple-mint scent. The flowers are pale pink and relatively small. It has been repeatedly introduced intentionally by humans for use in medicine, food preparations, essential oil, and as an ornamental plant. The leaves are also used for perfumery and linen pillows; it is used internally in the treatment of debility, gastroenteritis and hemorrhage. Externally, it is used to treat skin complaints, injuries, and neuralgia and throat infections. The essential oil is used in aromatherapy. It is also used in the treatment of burns, sores and shingles. The leaves are crushed and used to flavor salads, soups, fruit dishes, jellies, sorbets, ice cream, and cakes. This plant is easily propagated by cutting, but it faces some problems like slow growth, not rooting, and high losses due to fungal and bacterial contamination. So, a tissue culture technique was developed to rapid up the proliferation of this plant. This method has some advantages such as low-cost and mass production of plantlets with high quality and pathogen free in a short time.