سعید کدخدایی دکترای خود را در رشته مهندسی ژنتیک در سال 1393 از دانشگاه UPM اخذ نمود و دو دوره پسادکترا در زمینه بیوانفورماتیک و مهندسی ژنوم از طریق فناوری کریسپر به ترتیب در دانشگاه های UPM و صنعتی اصفهان (بنیاد ملی نخبگان) را با موفقیت به اتمام رساند. وی از سال 1381 فعالیت خود را در پژوهشکده بیوتکنولوژی کشاورزی منطقه مرکزی کشور و با همکاری در راه‌اندازی این مجموعه آغاز نمود. زمینه تحقیقاتی مورد علاقه ایشان استفاده از فناوری کریسپر به ویژه کاربرد آن در کیت های تشخیص مولکولی است.

 

- استفاده از فناوری کریسپر در شناسایی سریع ویروس‌های سیب‌زمینی

- استفاده از نشانگرهای مولکولی به منظور شناسایی سریع و دقیق توده های Medicago sativa ایران

- تهیه شناسنامه ژنتیکی بادام ایران

 

مقالات و کتب

کتب:

1. ویرایش ژنوم با فناوری کریسپر و کاربردهای آن در علوم زیستی. 1399. انتشارات دانشگاه تربیت مدرس

2. کشاورزی مولکولی. 1389. انتشارات پژوهشگاه بیوتکنولوژی کشاورزی

 

3. Cis/Transgene Optimization: Systematic discovery of novel gene expression elements. 2018. Springer

4. An Introduction to Synthetic biology: Design and Assembly of Genetic Constructs. 2015. eBook

:مقالات

 5. Talei D, Nekouei M, Kadkhdodaei S. 2022. Evaluation of genetic diversity of Nain Havandi plant masses based on protein and SRAP markers. JMBS. In Press.

6. Hosseini MS, Ebrahimi M, Abadia J, Kadkhodaei S, et al. 2022. Growth, phytochemical parameters and glycyrrhizin production in licorice (Glycyrrhiza glabra L.) grown in the field with saline water irrigation. Industrial Crops and Products 177, 114444. https://doi.org/10.1016/j.indcrop.2021.114444

7. Bande F, Arshad SS, Bejo MH, Omar AR, Moeini H, Kadkhodaei S, et al. Development and immunogenic potentials of chitosan-saponin encapsulated DNA vaccine against avian infectious bronchitis coronavirus. 2020. Microbial Pathogenesis. 149. 104560. 10.1016/j.micpath.2020.104560

8. Talei D, Nekouei M, Mardi M, Kadkhdodaei S. 2020. Improving productivity of steviol glycosides in Stevia rebaudiana via induced polyploidy. Journal of Crop Science and Biotechnology. 23(4). https://doi.org/10.1007/s12892-020-00038-5

9. Nekouei M, Moazam M, Mardi M, Kadkhdodaei S. 2020. Development of SSR Markers Associated with Biosynthesis Pathway of Steviol Glycosides in Stevia through De Novo Transcriptome Assembly. JMBS. 2020; 11 (2) :185-191

10. Monfared HH, Chew JK, Azizi P, Xue GP, Ee S, Kadkhodaei S, Hedayati P, Ismail I, Zainal Z. 2020. Overexpression of a Rice Monosaccharide Transporter Gene (OsMST6) Confers Enhanced Tolerance to Drought and Salinity Stress in Arabidopsis thaliana. Plant Mol Biol Rep. doi:10.1007/s11105-019-01186-x

11. Bahari MNA, Sakeh NM, Abdullah SNA, Ramli RR, Kadkhodaei S. 2018. Transciptome profiling at early infection of Elaeis guineensis by Ganoderma boninense provides novel insights on fungal transition from biotrophic to necrotrophic phase. BMC plant biology 18 (1), 377. doi:10.1186/s12870-018-1594-9

12. Kadkhodaei S, Hashemi F, Rezaei M, et al. 2018. Conceptual Models. In: Cis/Transgene Optimization. SpringerBriefs in Systems Biology. Springer, Cham. doi:10.1007/978-3-319-90391-0_4

13. Kadkhodaei S, Hashemi F, Rezaei M, et al. 2018. Outcomes Assessment. In: Cis/Transgene Optimization. SpringerBriefs in Systems Biology. Springer, Cham. doi: 10.1007/978-3-319-90391-0_3

14. Kadkhodaei S, Hashemi F, Rezaei M, et al. 2018. Systematic Strategies. In: Cis/Transgene Optimization. SpringerBriefs in Systems Biology. Springer, Cham. doi: 10.1007/978-3-319-90391-0_2

15. Ahmadi F, Abdullah SNA, Kadkhodaei S, Ijab S, Abdul Aziz M, Rahmane Z, Alwee SS. 2018. Functional characterization of the gene promoter for an Elaeis guineensis phosphate starvation-inducible, high affinity phosphate transporter in both homologous and heterologous model systems. Plant Physiology and Biochemistry, 127, 320–335. doi: 10.1016/j.plaphy.2018.04.004

16. Tan JS, Abbasiliasi S, Kadkhodaei S, Tam YJ, Tang T-K, Lee Y-Y, Ariff AB. 2018. Microtiter miniature shaken bioreactor system as a scale-down model for process development of production of therapeutic alpha-interferon2b by recombinant Escherichia coli. BMC Microbiology 18. doi: 10.1186/s12866-017-1145-9

17. Movahedi A, Zhang J, Sun W, Kadkhodaei S, Mohammadi K. 2018. Plant small RNAs: definition, classification and response against stresses. Biologia 1-10. doi: 10.2478/s11756-018-0034-5

18. Abbasiliasi S, Tan JS, Ibrahim TAT, Ramanan RN, Kadkhodaei S, Mustafa S, Ariff AB. 2018. Kinetic modeling of bacteriocin-like inhibitory substance secretion by Pediococcus acidilactici Kp10 and its stability in food manufacturing conditions. Journal of Food Science and Technoogyl. doi: 10.1007/s13197-018-3037-x

19. Yeng S, Abbasiliasi S, Keong C, Kadkhodaei S, Shamzi M, Hashim R, Shun J. 2018. Extraction of fresh banana waste juice as non-cellulosic and non-food renewable feedstock for direct lipase production. Renewable Energy 126:431–436. doi: 10.1016/j.renene.2018.03.050

20. Kadkhodaei S, Memari HR, Abbasiliasi S, Rezaei MA, Movahedi A, Tan JS, Ariff AB. 2016. Multiple overlap extension PCR (MOE-PCR): An effective technical shortcut to high throughput synthetic biology. RSC Advances. Royal Society of Chemistry. DOI: 10.1039/C6RA13172G.

21. Sofijan H, Joo Shun T, Abbasiliasi S, Mustafa S, Puspaningsih N, Kadkhodaei S, Ariff AB. 2016. Recovery and partial purification of thermophilic β-xylosidase derived from recombinant Bacillus megaterium MS941 by aqueous two-phase system. Separation Science and Technology. DOI: 10.1080/01496395.2016.1268159

22. Bande F, Arshad SS, Bejo MH, Kadkhodaei S, Omar AR. 2016. Prediction of B-cells and T-cells epitopes in the spike glycoprotein of M41 and CR88 avian infectious bronchitis virus strains for application in peptide vaccine. Advances in Bioinformatics, DOI:10.1155/2016/5484972.

23. Bamaiyi PH, Izreen MS, Khatijah M, Eizzati BH, Bainum CR, Farhana MK, Norfaizul MN, Kadkhodaei S, Khan GK. 2016. Isolation and polymerase chain reaction identification of bacteria from the 2014–2015 flood of Kota Bharu, Kelantan, Malaysia. Asian Biomedicine, 10:6, 549–565. DOI: 10.5372/1905-7415.1006.525

24. Abbasiliasi S, Tan JS, Kadkhodaei S, Nelofer R, Ibrahim TAT, Mustafa S, Ariff AB. 2016. Enhancement of BLIS production by Pediococcus acidilactici kp10 in optimized fermentation conditions using an artificial neural network. RSC Advances. 6 (8), 6342-6349.

25. Kadkhodaei S, Barantalab F, Taheri S, Foroughi M, Hashemi FG, Shabanimofrad MR, et al. 2015. BioInfoBase: A Bioinformatics Resourceome. arXiv: Cornel University Library. 1607.02974v1.

26. Kadkhodaei S, Abbasiliasi S, Tan JS, Fard Masoumi HR, Mohamed MS, Rahim R, Ariff AB. 2015. Enhancement of protein production by microalgae Dunaliella salina under mixotrophic condition using response surface methodology. RSC Advances. DOI: 10.1039/C5RA04546K.

27. Movahedi A, Zhang J, Gao P, Yang Y, Wang L, Yin T, Kadkhodaei S, Ebrahimi M, Zhuge Q. 2014. Expression of the chickpea CarNAC3 gene enhances salinity and drought tolerance in transgenic poplars. Plant Cell, Tissue and Organ Culture. 1-14.

28. Mohamed MS, Tan JS, Kadkhodaei S, Mohamad R, Mokhtar MN, Ariff AB. 2014. Kinetics and modeling of microalga Tetraselmis sp. FTC 209 growth with respect to its adaptation toward different trophic conditions. Biochemical Engineering Journal. 88:30–41.

29. Tan JS, Abbasiliasi S, Lin YK, Mohamed MS, Kapri MR, Kadkhodaei S, Tam YJ, Rahman RNZRA, Ariff AB. 2014. Primary recovery of thermostable lipase 42 derived from recombinant Escherichia coli BL21 in aqueous two-phase flotation. Separation and Purification Technology. 133:328–334.

30. Abbasiliasi S, Tan JS, Ibrahim TAT, Kadkhodaei S, Ng HS, Vakhshiteh F, Ajdari Z, Mustafa S, Ling TC, Rahim RA, Ariff AB. 2014. Primary recovery of a bacteriocin-like inhibitory substance derived from Pediococcus acidilactici Kp10 by an aqueous two-phase system. Food Chemistry. 151:93–100.

31. Ghaderi-Zefrehei M, Memari H, Kadkhodaei S. 2010. Multilevel modeling in human microarray time course gene expression data. 1-5. doi: 10.1109/ICBME.2010.5705026.

32. Ebrahimi M, Pezashki A, Nekouei MK, Kadkhodaei S. 2013. Investigation effect of kind and concentration of sodium alginate encapsulation in germination and growth of alfalfa artificial seed. Agronomy Journal (Pajouhesh & Sazandegi). 101: 48-59.

33. Kadkhodaei S, Nekouei MK, Shahnazari M, Etminani H, Imani A, Ghaderi-Zefrehei M, Elahy M, Ariff AB. 2011. Molecular tagging of agronomic traits using simple sequence repeats: Informative markers for almond (Prunus dulcis) molecular breeding. Australian Journal of Crop Science. 5:1199–1209.

34. Kadkhodaei S, Shahnazari M, Nekouei MK, Ghasemi M, Etminani H, Imani A, Ariff AB. 2011. A comparative study of morphological and molecular diversity analysis among cultivated almonds (Prunus dulcis). Australian Journal of Crop Science. 5:82–91.

35. Kadkhodaei S, Elahy M, Nekouei MK, Imani A, Shahnazari M, Mardi M, Javanmard A, Ariff AB. 2010. A panel of cultivate specific marker based on polymorphisms at microsatellite markers for Iranian cultivated Almonds (Prunus dulcis). Australian Journal of Crop Science. 4:730–736.

36. Pezeshki A, Ebrahimi M, Nekouei MK, Kadkhodaei S. 2010. Effects of several plant growth regulators, carbon source and amino acids on somatic embryos obtained from embryogenic cell suspension culture of alfalfa (Medicago sativa L.). Iranian Journal of Rangelands and Forests Plant Breeding and Genetic Research. 18(1):63-73.

37. Ebrahimi M, Nekouei MK, Kadkhodaei S. 2009. Study of Some Factors Influencing Embryogenesis and Maturation of Soybean (Glycine max) Somatic Embryos. Journal of Water and Soil Science. 12(46): 167-176.

38. Fathi A, Ghareyazi B, Haghnazari A, Ghaffari MR, Pirseyedi SM, Kadkhodaei S, Naghavi MR, Mardi M. 2008. Assessment of the genetic diversity of almond (Prunus dulcis) using microsatellite markers and morphological traits. Iranian Journal of Biotechnology. 6(2):98-106.

39. Kadkhodaei S, Aghdaei SRT, Grigorian V, Moghadam M, Hashemi SMM. 2006. A study on genetic variation among some wild almond species using RAPD markers. Acta Hortic 93–98.

40. Siahmard M, Daneshvar MH, Memari HR, Ardekani MR, Kadkhodaei S. 2012. Cloning of human gama INF in an expression vector for microalgae transformation. Modern Genetics Journal. 4:10.

41. Kadkhodaei S, Aghdaei RT. 2002. Optimizing DNA extraction procedure in case of Amygdalus spp.: A simple and inexpensive method for nucleic acid isolation from plants with high polysaccharides and polyphenolic compounds. Iranian Journal of Rangelands and Forests Plant Breeding and Genetic Research. 10(10):15-27.

42. Kadkhodaei S, Tabaei Aghdaei SR, Gerigourian V, Moghadam Mohammad M. 2002. Genetic diversity analysis among wild almond populations of Esfahan province using RAPD markers. Iranian Journal of Horticultural Science and Technology. 3(4):25-36.